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About us

We are located in the Division of Signaling and Functional Genomics at the German Cancer Research Center (DKFZ) in Heidelberg.

Fillip Port, PhD

Fillip started CRISPR fly design in 2013, initially as a side project during his postdoc at the Laboratory of Molecular Biology in Cambridge. In 2016 he took the project to the Division of Signaling and Functional Genomics at the DKFZ, where he continues to develop and apply Drosophila CRISPR tools for functional genomics. He maintains the website and you can contact him with any questions or comments by email or follow him on Twitter.
Fillip studied biology in Freiburg, did a PhD with Koni Basler in Zurich studying Wnt secretion and a postdoc with Simon Bullock in Cambridge working on mRNA localisation and CRISPR method development. He is from a small village in central Germany.

Michael Boutros, PhD

Michael is head of the Division of Signaling and Functional Genomics at the German Cancer Research Center (DKFZ). His lab is studying signaling networks in development and cancer. A particular focus of the group is on high-throughput methods for systematic functional analysis of cellular processes to identify vulnerabilities of cancer cells. Learn more about our work here.
Michael did a PhD with Marek Mlodzik at EMBL and a postdoc with Norbert Perrimon at Harvard Medical School. He established his lab at the DKFZ in 2003 and since 2008 is head of the Functional Genomics Division and full professor at Heidelberg University.

Claudia Strein

Claudia trained as a technician at the DKFZ Heidelberg graduating in 1993. After working in two pharma companies she joined Matthias Hentze’s lab at EMBL. There she worked on developing the novel ‘interactome capture method’ to identify RNA-binding proteins.In 2013 she joined the Division of Signaling and Functional Genomics at the DKFZ, where she worked on a genome-wide RNAi screen in Drosophila melanogaster. In 2016 she joined the CRISPRflydesign team to develop systematic resources for CRISPR knock-out screening.

Mona Stricker

Mona trained as a medical technical assistant at the Theresienhospital in Mannheim. Afterwards she worked on autoantibodies with Dr. Seelig in Karlsruhe and at the German Resource Center for Genome Research in Heidelberg. She joined the DKFZ in 2001 and the Division of Signaling and Functional Genomics in 2004. In 2016 she joined our team to help build our transgenic gRNA library. After the lab she loves indoor cycling to take her mind off work.

Amélie Pöltl

Amélie is doing a gap year in the lab in order to gain insights into research related professions. She is characterizing different genome editing systems by performing various experiments, such as genotyping, phenotypic screens or mutation calling. Together with Eva she is also maintaining most of our Drosophila collection.



Eva Roßmanith

Also Eva is doing a gap year to gain practical experience in the lab. She is investigating CRISPR methods in Drosophila using various techniques, such as PCR, in-situ hybridization and antibody stainings. Together with Amélie she is also helping to organize the lab and to maintain our fly strains.


Martha Buhmann

Martha is part of the MSc Molecular Biosciences program at the University of Heidelberg. She joined the CFD team for her Master’s thesis where she is focusing on the application of our CRSISPR tools in new tissue contexts. Before coming to Heidelberg, Martha obtained a BSc degree in Biomedical Sciences from the University of Marburg.



Roman Doll

Roman has studied for a BSc in Molecular Biomedicine in Bonn before entering the MSc Molecular Biosciences program at Heidelberg University. He has joined the CFD team for his master thesis, in which he is establishing new genome editing tools and comparing their capabilities to existing technologies.


Join us! If you are interested to join our team and develop and apply new CRISPR technologies than please contact Fillip or Michael informally to discuss possibilities.


Ann-Christin Michalsen (09/21-08/22)
Alexander Kremer (09/21-08/22)
Laura Lange (09/19 – 08/20)
Nora Langner (09/19 – 08/20)
Ainoa Tejedera (05/19 – 08/19)
Amy Hess (09/18 – 08/19)
Celine Beyersdörffer (09/18 – 06/19)
Maja Starostecka (11/17 – 10/18)
Roberta Malamud (09/17 – 08/18)

Lukas Schmitt (09/17 – 06/18)
Kristin Rädecke (01/18 – 03/18)
Lukas Voos (09/16 – 08/17)
Katharina Kern (09/16 – 07/17)
Jana Frei (09/2016 – 04/2017)
Mariane Dahmer (02/2017 – 03/2017)

Anni, Martha, Alex, Roman, Fillip, Claudia
The CFD team 2019/2020: Nora, Laura, Mona, Claudia, Fillip
The CFD team 2018/2019: Claudia, Celine, Fillip, Amy, Mona
The CFD team 2016/2017: Mona, Jana, Katharina, Claudia, Fillip, Lukas